MyBioSource.com's phospho-Sox2 (S246) Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Dot Blot, ELISA, and Immunofluorescence. The phospho-Sox2 (S246) Antibody was generated using lcc, SOX2, and SRY box 2 as the antigen and it reacts with Human.
Description
This intronless gene encodes a member of the SRY-related
HMG-box (SOX) family of transcription factors involved in the
regulation of embryonic development and in the determination of
cell fate. The product of this gene is required for stem-cell
maintenance in the central nervous system, and also regulates gene
expression in the stomach. Mutations in this gene have been
associated with optic nerve hypoplasia and with syndromic
microphthalmia, a severe form of structural eye malformation. This
gene lies within an intron of another gene called SOX2 overlapping
transcript (SOX2OT)